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Clinical study of the Immunoglobululin Enhancing effect of "Bala compound" on Infants
Rao R Appaji1, R D Sharma, G P Katiyar
1Head of Dept Prasooti, Stree Roga and Bala roga, Dr.N .R. S. Govt. Ay. College, Vijayawada, India.
Insights
This study investigated the effects of the Ayurvedic "Bala compound" on infant immunity. Six months of oral administration significantly increased key serum immunoglobulins (IgG, IgM, IgA) in infants, suggesting improved immune function.
Area of Science:
- Ayurvedic Medicine
- Pediatric Health
- Immunology
Background:
- Kaumarbhritya, an Ayurvedic branch, focuses on child health.
- High infant mortality rates (I.M.R.) in developing countries are often caused by infections.
- Neonatal immune systems are immature and vulnerable.
Purpose of the Study:
- To evaluate the impact of an Ayurvedic formulation, the "Bala compound", on infant immune markers.
- To assess changes in serum immunoglobulin levels in infants receiving the Bala compound.
Main Methods:
- The Bala compound, containing several Ayurvedic herbs, was administered orally to infants.
- Serum immunoglobulin levels (IgG, IgM, IgA) were measured at baseline and after three and six months.
- A multicentric study design was employed.
Main Results:
- Significant increases in serum IgG, IgM, and IgA levels were observed after six months of Bala compound administration.
- The study demonstrated a positive effect on the developing immune system.
Conclusions:
- The Bala compound shows potential as an immunomodulatory agent for infants.
- This Ayurvedic intervention may help bolster infant immunity against infections, potentially reducing I.M.R.
Abstract:
Kaumarbhritya a branch of Asthanga Ayurveda deals with neonatal, infant and child health care. Multicentric studies conducted in various developed and developing countries have indicated that Infant Mortality Rate (I.M.R.) is very high in developing countries, and infection has been observed as the major cause. Immune system in neonates is not yet fully functional. Bala compound having the ingredients ofAtibala (Abutilon indicum Linn), Amalaki (Emblica officinalis Linn), Vidanga (Emblica ribes burn), Guduchi (Tinospora cordifolia Welld Miers), Pippali (Piperlongum linn), Yashtimadhu (Glycyrrhiza glabra Linn), Shankhapuspi (Convolvulus pluricaulis Chois ), Vacha (Acorus calamus Linn), Musta (Cyperus rotundus Linn) and Ativisha (Aconitum heterophyllum wall) are Medhya as well as Rasayana drugs mention in Ayurvedic classics. 'Bala compound" was tried in infants in the form of oral drops for a period of six months and result was assessed for serum immuoglobulins IgG, IgM, IgA for three months of interval of two follow ups (i.e., third and six month of infant). There is significant increase of immunoglobulins observed after six months administration of 'Bala compoumd"
