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Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

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Antibacterial activity on Citrullus colocynthis Leaf extract.

S Shyamala Gowri¹, S Priyavardhini, K Vasantha

¹Ph.D. Research Scholar, Department of Botany, Kongunadu Arts and Science (Autonomous) College, G. N. Mills, Coimbatore 29, TamilNadu, India.

Ancient Science of Life

|May 5, 2012

Summary

Citrullus colocynthis leaf extract shows antibacterial potential. The crude acetone extract effectively inhibited Pseudomonas aeruginosa, highlighting its medicinal value.

Keywords:

Citrullus colocynthis agar disc diffusion and antibacterial activity

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

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Thin-layer Chromatographic (TLC) Separations and Bioassays of Plant Extracts to Identify Antimicrobial Compounds

Thin-layer Chromatographic (TLC) Separations and Bioassays of Plant Extracts to Identify Antimicrobial Compounds

Published on: March 27, 2014

Area of Science:

Pharmacology and Phytochemistry
Microbiology

Background:

Citrullus colocynthis (Cucurbitaceae) is a traditional medicinal plant.
Its leaf extract is utilized for treating diverse health conditions.

Purpose of the Study:

To investigate the antibacterial properties of Citrullus colocynthis leaf extracts.
To determine the efficacy against specific bacterial pathogens.

Main Methods:

Agar disc diffusion technique was employed.
Antibacterial activity was assessed using crude acetone and chloroform leaf extracts.

Main Results:

The crude acetone extract demonstrated significant antibacterial activity against Pseudomonas aeruginosa, with a 14.0mm zone of inhibition.
No antibacterial activity was observed against Staphylococcus aureus with the chloroform extract.
The minimum inhibitory concentration for the chloroform extract against Escherichia coli was determined.

Conclusions:

Citrullus colocynthis leaf extracts possess notable antibacterial properties.
The crude acetone extract is particularly effective against Pseudomonas aeruginosa.
Further research is warranted to explore its therapeutic applications.