Pre and post-implantation changes in the uteus of rats: response to moringa oleifera lam. Extract

Aqueous extract of Moringa oleifera Lam. (root) has been studies on pre and post-implementation stages of the uterus of rats so as to elucidate its antifertility mode of action. Results on the biochemical estimation in the uterus of control pregnant rats at different stages of pregnancy revealed a successive increase in the total proteins, glycogen content and the activity or acid and alkaline phosphatase from day 2 to 5 post-coitum. When aqueous extract of M. oleifera Lam. Was administered, there was a significant reduction in all these biochemical constituents when compared to their respective control groups. The role of these biochemical transformations has been discussed in relation to anti-implantation action of the extract.