Related Experiment Videos
Retroperitoneal involvement in sarcoidosis.
P Fraioli1, L Montemurro, L Castrignano
1Sarcoidosis Clinic, Niguarda Hospital, Milan, Italy.
Sarcoidosis
|September 1, 1990
Summary
Retroperitoneal lymph nodes are common in sarcoidosis. This study highlights previously unreported complications like hydronephrosis, urine retention, and jaundice caused by lymph node compression in sarcoidosis patients.
Area of Science:
- Nephrology
- Gastroenterology
- Oncology
Background:
- Retroperitoneal lymphadenopathy is a recognized manifestation of sarcoidosis.
- However, the compressive effects of these lymph nodes on adjacent organs are less commonly reported.
Observation:
- Two patients presented with unilateral hydronephrosis, one asymptomatic and one with dysuria.
- One patient experienced urine retention due to bilateral ureteral compression and jaundice from biliary tract compression.
- Four additional patients showed retroperitoneal lymphadenopathy without signs of organ compression.
Findings:
- Retroperitoneal lymph node enlargement in sarcoidosis can lead to significant complications.
- These complications include urinary tract obstruction (hydronephrosis, urine retention) and biliary tract obstruction (jaundice).
Implications:
- Retroperitoneal impairment should be considered a potential complication of sarcoidosis.
- This underscores the importance of evaluating for compressive effects in patients with sarcoidosis and retroperitoneal lymphadenopathy.