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Published on: September 20, 2018
Childhood microbial keratitis
Abdullah G Al Otaibi1, Khalid Allam, Al Johara Damri
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Insights
Pediatric microbial keratitis, often caused by trauma, requires prompt evaluation and treatment. Early diagnosis and management are crucial for favorable visual outcomes in children.
Area of Science:
- Ophthalmology
- Microbiology
- Pediatrics
Background:
- Microbial keratitis is a serious eye infection that can lead to vision loss.
- Pediatric cases present unique challenges in diagnosis and management.
- Understanding risk factors and causative agents is vital for effective treatment.
Purpose of the Study:
- To identify risk factors associated with pediatric microbial keratitis.
- To describe the clinical presentation, microbial spectrum, and treatment outcomes.
- To evaluate visual prognosis in children diagnosed with microbial keratitis.
Main Methods:
- Retrospective review of medical records for children (≤16 years) with microbial keratitis.
- Data collected included demographics, predisposing factors, clinical course, and microbial cultures.
- Analysis of treatment modalities and visual outcomes at a tertiary referral eye hospital.
Main Results:
- Ocular trauma was the leading predisposing factor (39.7%) in 68 pediatric cases.
- Gram-positive bacteria, particularly Streptococcus pneumoniae, were the most common isolates.
- 50% of cases had positive microbial cultures, with 66.2% achieving a best-corrected visual acuity of 20/40 or better.
Conclusions:
- Prompt and comprehensive management is essential for pediatric microbial keratitis.
- Identifying predisposing factors and causative organisms aids in successful treatment.
- Ocular trauma is a significant risk factor, emphasizing the need for preventative measures.
Purpose:
To evaluate risk factors for pediatric microbial keratitis and to describe the clinical picture, microbial spectrum, treatment modalities, posttreatment sequelae, and visual outcome in cases with pediatric microbial keratitis.
Materials And Methods:
All cases of microbial keratitis that occurred in children 16 years or younger who had an initial examination between January 2000 and December 2010 at a tertiary referral eye hospital in Riyadh, Saudi Arabia, were identified. A retrospective review of medical records was conducted using a computer-based diagnosis code. Demographic data, predisposing factors, clinical course, microbial culture results, and visual outcomes were recorded.
Results:
Sixty-eight eyes were included in this study. Predisposing factors were identified in 63 eyes (92.6%). All patients had unilateral microbial keratitis. The mean±SD age was 4.5 ± 4.8 years and 57.4% were male. Trauma was the leading cause [27 eyes (39.7%)], followed by systemic diseases [14 eyes (20.6%)], contact lens wear [11 eyes (16.1%)], and ocular diseases [11 eyes (16.1%)]. Corneal scraping was performed in all cases. Five patients needed general anesthesia to carry out the corneal scraping. Thirty-four (50.0%) eyes showed positive cultures. Gram-positive bacteria accounted for 67.8% and gram-negative bacteria for 38.2% of isolates. Streptococcus pneumoniae was the most commonly isolated organism [8 eyes (25.8%)], followed by Staphylococcus epidermidis [7 eyes (22.7%)]. Pseudomonas aeruginosa was the most commonly isolated gram-negative [6 eyes (17.6%)] organism. One eye had corneal perforation and required surgical intervention. Forty-five of 68 eyes (66.2%) had a best-corrected visual acuity evaluation at the last follow-up and 28 eyes (62.2%) of them had a best-corrected visual acuity of 20/40 or better.
Conclusion:
Children with suspected microbial keratitis require comprehensive evaluation and management. Early recognition, identifying the predisposing factors and etiological microbial organisms, and instituting appropriate treatment measures have a crucial role in outcome. Ocular trauma was the leading cause of childhood microbial keratitis in our study.
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