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Related Experiment Video

Updated: May 22, 2026

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Published on: October 18, 2012

Lesions on tattooed skin--a case study.

Emiliano Grillo¹, Marta Urech, Sergio Vano-Galvan

¹Department of Dermatology, Ramon y Cajal University Hospital, Madrid, Spain. doctor-grillo85@hotmail.com

Australian Family Physician

|May 5, 2012

Summary

A 33-year-old man developed asymptomatic papules on tattooed skin. These lesions, appearing 5 months post-tattooing, were diagnosed as lichen planus, a common inflammatory condition.

Area of Science:

Dermatology
Cutaneous Manifestations
Inflammatory Skin Conditions

Background:

Tattooing is a prevalent practice globally.
Skin reactions to tattoo pigments can occur, necessitating accurate diagnosis.
Understanding the spectrum of tattoo-associated dermatoses is crucial for clinical management.

Observation:

A 33-year-old male presented with asymptomatic, shiny, umbilicated papules (3–4 mm) on tattooed skin of the right upper arm.
The lesions appeared spontaneously 5 months after tattoo application.
No significant past medical or surgical history was reported; standard infectious disease and blood tests were negative.

Findings:

The clinical presentation and morphology of the papules on tattooed skin are consistent with a diagnosis of lichen planus.

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Lichen planus is an immune-mediated inflammatory condition affecting skin and mucous membranes.

The tattoo serves as a potential trigger or localization site for the development of lichen planus (Koebner phenomenon).

Implications:

This case highlights lichen planus as a possible dermatological reaction to tattoo pigments.
Clinicians should consider lichen planus in the differential diagnosis of new skin lesions appearing on tattooed areas.
Further investigation into tattoo pigment composition and immune responses may elucidate the pathogenesis of such reactions.