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Updated: May 22, 2026
08:58
Fluorimetric Techniques for the Assessment of Sperm Membranes
Published on: November 28, 2018
Sperm head vacuoles--light microscopic and ultrastructural observations: a case report
Shucheng Zhang1, Ning Wang, Bin He
1National Research Institute for Family Planning, Beijing, People's Republic of China.
Ultrastructural Pathology
|May 8, 2012
Summary
This study reports a rare case of male infertility caused by 100% vacuolated sperm heads. These sperm head vacuoles are linked to abnormal sperm development and chromatin structure, impacting fertility.
Area of Science:
- Reproductive Biology
- Human Genetics
- Spermatozoa Ultrastructure
Background:
- Sperm head vacuoles are detectable via electron microscopy.
- Vacuoles exceeding 20% of head area are abnormal.
- This case presents primary spermatozoa deformity with 100% vacuolated heads.
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