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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
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Intracranial MPNST with multivacuolated cells and hyaline globules: a case with ultrastructural findings

Young Eun Kim1, Yeon-Lim Suh, Seung Eun Lee

  • 1Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Ultrastructural Pathology
|May 8, 2012
PubMed

Insights

This study reports a rare case of intracranial malignant peripheral nerve sheath tumor (MPNST) that recurred with unusual features. The recurrent tumor showed characteristics of undifferentiated sarcoma, differing from the primary MPNST.

Area of Science:

  • Neuro-oncology
  • Surgical Pathology
  • Electron Microscopy

Background:

  • Malignant peripheral nerve sheath tumors (MPNSTs) are rare and aggressive neoplasms.
  • Intracranial MPNSTs are exceptionally uncommon, and their recurrent behavior can present unique challenges.

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