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Water-equivalent path length calibration of a prototype proton CT scanner.

R F Hurley¹, R W Schulte, V A Bashkirov

¹Loma Linda University, Loma Linda, CA 92354, USA. fhurley@dominion.llumc.edu

Medical Physics

|May 8, 2012

Summary

This study introduces a straightforward calibration method for proton computed tomography (pCT) scanners. The new technique accurately measures relative stopping power (RSP) for tissue-equivalent materials, crucial for pCT imaging.

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Area of Science:

Medical Imaging
Particle Physics
Radiological Sciences

Background:

Accurate proton computed tomography (pCT) relies on precise energy detection.
Calibration of the energy detector is critical for measuring residual proton energy.
A prototype pCT scanner utilizes a cesium iodide (CsI(Tl)) crystal calorimeter.

Purpose of the Study:

To present a calibration method for a prototype proton computed tomography (pCT) scanner.
To ensure the accuracy of energy measurements for protons passing through an object.
To validate the calibration method by comparing measured relative stopping power (RSP) values.

Main Methods:

Calibrated a prototype pCT scanner using 200 and 100 MeV protons with polystyrene plates.
Generated calibration curves by fitting polynomials to water-equivalent path length versus calorimeter response data.
Measured RSP values of tissue-equivalent materials and reconstructed a water phantom's RSP distribution.

Main Results:

Measured RSP values for tissue-equivalent materials agreed within 0.5% of established water-tank methods.
The reconstructed water phantom's mean RSP value was 0.995 ± 0.006.
Demonstrated high accuracy in RSP measurements and reconstructions.

Conclusions:

The presented method offers a simple and reliable procedure for pCT scanner calibration.
This calibration technique is essential for accurate pCT imaging.
The method ensures precise measurement of proton energy and material properties.