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PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN.

Ylenia Bosio1, Gaia Berto, Paola Camera

  • 1Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Turin, Italy.

European Journal of Cell Biology
|May 8, 2012
PubMed
Summary

PPP4R2, a protein phosphatase 4 regulatory subunit, interacts with Survival of Motor Neuron (SMN) protein. This interaction is crucial for neuronal differentiation and survival, offering new insights into spinal muscular atrophy (SMA) pathogenesis.

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