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Updated: May 22, 2026

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
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Published on: January 5, 2016

Analysis of colonic alpha-synuclein pathology in multiple system atrophy

Hélène Pouclet1, Thibaud Lebouvier, Emmanuel Coron

  • 1Inserm, U913, Nantes F-44093, France; Inserm, CIC-04, Nantes F-44093, France; CHU Nantes, Department of Neurology, F-44093, France.

Parkinsonism & Related Disorders
|May 8, 2012
PubMed
Summary

Alpha-synuclein aggregates in the enteric nervous system (ENS) were investigated in multiple system atrophy (MSA). While less frequent than in Parkinson's disease (PD), these deposits were found in some MSA patients, indicating ENS involvement.

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