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Updated: May 22, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Chikungunya fever.

Eugene J Kucharz¹, Ilona Cebula-Byrska

¹Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland. ejkucharz@poczta.onet.pl

European Journal of Internal Medicine

|May 8, 2012

Summary

This summary is machine-generated.

Chikungunya fever (CF), a mosquito-borne viral illness, is spreading globally due to viral mutations. While typically self-limiting, CF can cause debilitating long-term arthritis, posing a significant public health concern.

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Published on: May 31, 2020

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Last Updated: May 22, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Area of Science:

Medical Entomology
Virology
Infectious Diseases

Background:

Chikungunya virus (CHIKV) causes Chikungunya fever (CF), an acute illness transmitted by Aedes mosquitoes.
CF is endemic in tropical regions but has recently emerged in Europe due to viral genome mutations enabling transmission by Aedes albopictus.
The disease presents with fever, rash, and severe joint pain, with potential for neurological or hemorrhagic complications.

Purpose of the Study:

To summarize the epidemiology, clinical manifestations, and public health implications of Chikungunya virus (CHIKV) infections.
To highlight the emergence of CHIKV in non-tropical regions, particularly Europe, and its associated risk factors.
To discuss current treatment and prevention strategies for Chikungunya fever (CF).

Main Methods:

Literature review of Chikungunya virus (CHIKV) epidemiology and clinical studies.
Analysis of recent outbreaks and viral adaptation in European countries.
Synthesis of information on disease symptoms, complications, and management.

Main Results:

Chikungunya virus (CHIKV) outbreaks have been reported in Europe, linked to mutations facilitating Aedes albopictus transmission.
Clinical manifestations include acute fever, rash, and severe arthralgia, with some patients developing chronic arthritis.
Neurological and hemorrhagic complications can occur in severe cases.

Conclusions:

Chikungunya fever (CF) represents a growing global health threat, including in European countries, due to increased viral transmission.
Effective prevention strategies focus on mosquito control and personal protection.
Vaccine development is ongoing, but currently, only symptomatic treatment is available for CF.