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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
07:18

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Published on: June 13, 2019

Interdigitating dendritic cell sarcoma occured alone in axilla.

Sun Wook Han1, Zi Sun Kim, Hyuk Moon Kim

  • 1Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea.

Journal of the Korean Surgical Society
|May 8, 2012
PubMed
Summary
This summary is machine-generated.

Interdigitating dendritic cell sarcoma (IDCS) is a rare and aggressive cancer. This case study details a patient successfully treated with radiotherapy for axillary IDCS, showing no recurrence after 13 months.

Keywords:
AxillaInterdigitating dendritic cell sarcoma

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Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
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Area of Science:

  • Oncology
  • Pathology

Background:

  • Interdigitating dendritic cell sarcoma (IDCS) is an exceptionally rare and aggressive neoplastic disease.
  • Diagnosis and treatment of IDCS present significant challenges due to its rarity and rapid progression.

Observation:

  • A 57-year-old female presented with a hard, fixed left axillary mass.
  • Computed tomography revealed a 7 cm left axillary lymph node; core biopsy suggested sarcoma.

Findings:

  • Pathological examination following left axillary lymph node dissection confirmed Interdigitating dendritic cell sarcoma.
  • The patient received radiotherapy as the sole treatment for the axillary IDCS.

Implications:

  • The patient remained recurrence-free for 13 months post-radiotherapy, indicating a potential treatment avenue.
  • Further research and accumulated clinical experience are crucial for establishing optimal treatment strategies for IDCS.