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Hypertension and antihypertensive treatment in HIV-infected individuals. A longitudinal cohort study

Ingjerd W Manner1, Morten Baekken, Olav Oektedalen

  • 1Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway. i.w.manner@medisin.uio.no

Blood Pressure
|May 9, 2012
PubMed

Insights

Hypertension is common in HIV patients, with longer HIV duration increasing risk. While antihypertensive treatment use rose, better blood pressure control is still needed.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Hypertension is a major risk factor for cardiovascular disease, particularly in individuals with HIV.
  • Understanding hypertension development and management in HIV-infected populations is crucial.

Purpose of the Study:

  • To assess the incidence of new-onset hypertension in HIV-infected individuals.
  • To evaluate the use of antihypertensive treatments and blood pressure control in this cohort.

Main Methods:

  • A longitudinal study followed 434 HIV-infected individuals over 3.4 years.
  • Standardized blood pressure measurements and cardiovascular risk factor monitoring were performed.
  • Multiple logistic regression analysis identified predictors of new-onset hypertension.

Main Results:

  • New-onset hypertension occurred at an incidence of 29.8 per 1000 person-years.
  • HIV duration, mean blood pressure, and abnormal urinary albumin excretion were independent predictors.
  • Antihypertensive treatment use increased threefold, but only 22% achieved adequate blood pressure control.

Conclusions:

  • Longer HIV duration is a predictor of new-onset hypertension, potentially linked to low-grade inflammation.
  • Despite increased treatment, enhanced awareness and management of hypertension in HIV-infected individuals are necessary.
Abstract

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