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Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
The Scientific Method in Nursing Process01:18

The Scientific Method in Nursing Process

The scientific method provides the foundation for any research. It is the most reliable and objective of all forms of gaining knowledge and guides in applying research-based evidence in practice and conducting future research.
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be safely...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
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All animals have varying degrees of...

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Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

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Published on: January 10, 2025

Consensus principles for wound care research obtained using a Delphi process.

Thomas Serena1, Barbara Bates-Jensen, Marissa J Carter

  • 1Wound and Hyperbaric Centers, The Serena Group, 90 Sherman St., Cambridge, MA 02140, USA.

Wound Repair and Regeneration : Official Publication of the Wound Healing Society [And] the European Tissue Repair Society
|May 9, 2012
PubMed
Summary
This summary is machine-generated.

This study developed 19 consensus-based principles to improve the design, execution, and reporting of wound healing research. These guidelines aim to enhance the quality and consistency of clinical and comparative effectiveness studies in wound care.

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Area of Science:

  • Wound Healing Research
  • Clinical Research Methodology
  • Comparative Effectiveness Research

Background:

  • Numerous wound care research studies suffer from poor design, execution, and data quality.
  • This deficiency impacts the reliability and applicability of findings in clinical practice.
  • A need exists for standardized principles to guide research in this field.

Purpose of the Study:

  • To establish a set of consensus-driven principles for stakeholders in wound healing research.
  • To enhance the quality of clinical and comparative effectiveness studies in wound care.

Main Methods:

  • A Delphi approach was employed to achieve expert consensus.
  • Utilized web-based surveys for 115 wound care researchers and face-to-face conferences for an 11-member expert panel.
  • Principles were refined through iterative rounds of rating and feedback using 5-point Likert scales.

Main Results:

  • Developed 19 final principles for wound healing research after two rounds of Delphi consensus.
  • Initial principles underwent revision based on expert and researcher feedback, with high endorsement rates.
  • The final principles address variations in study design, conduct, and reporting.

Conclusions:

  • The established principles provide a framework for improving the standard of wound care research.
  • Implementation of these guidelines is expected to enhance the quality and consistency of research in wound healing.
  • These principles will aid researchers, clinicians, and other stakeholders in conducting more robust studies.