Related Experiment Video
Updated: May 22, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Complexity generation during natural product biosynthesis using redox enzymes
1Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, United States.
Abstract:
Redox enzymes such as FAD-dependent and cytochrome P450 oxygenases play indispensible roles in generating structural complexity during natural product biosynthesis. In the pre-assembly steps, redox enzymes can convert garden variety primary metabolites into unique starter and extender building blocks. In the post-assembly tailoring steps, redox cascades can transform nascent scaffolds into structurally complex final products. In this review, we will discuss several recently characterized redox enzymes in the biosynthesis of polyketides and nonribosomal peptides.
Related Concept Videos
Redox Reactions
Redox Reactions
The Supercomplexes in the Crista Membrane
Redox Equilibria: Overview
Electron Transport Chain: Complex III and IV
Biosynthesis in Bacteria
