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Related Experiment Videos

[Pain after sympathectomy].

J M Farcot1, C Grasser, J F Muller

  • 1Clinique de la Toussaint, Strasbourg.

Agressologie: Revue Internationale De Physio-Biologie Et De Pharmacologie Appliquees Aux Effets De L'Agression
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

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Surgical sympathectomy can cause painful radiculalgia due to nerve deafferentation. Membrane stabilizers like nifedipine effectively treat this pain by improving neurovascular function.

Area of Science:

  • Neurosurgery
  • Pain Management
  • Autonomic Nervous System

Context:

  • Surgical sympathectomy and chemical sympatholysis induce sympathetic deafferentation.
  • This can lead to retrograde degeneration of pre-ganglionic neurons and neurovascular disorders.
  • A rare complication is the development of radiculalgia-like painful syndromes.

Purpose:

  • To describe the characteristics and outcomes of radiculalgia following sympathetic denervation procedures.
  • To investigate the efficacy of different therapeutic approaches for managing this specific pain syndrome.

Summary:

  • Forty-seven cases of radiculalgia were reported, characterized by sudden onset, often nocturnal pain.
  • The condition typically resolves spontaneously with gradual recovery of peripheral vasomotor tone.

Related Experiment Videos

  • While conventional analgesics are ineffective, membrane stabilizers (e.g., nifedipine) show promise in alleviating symptoms.

    • Impact:

    • Identifies a specific functional pain syndrome following sympathectomy.
    • Suggests nifedipine as a potential treatment for improving neurovascular function and reducing pain.
    • Highlights the importance of considering prior calcium channel blocker use when administering nifedipine post-sympathectomy.