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Related Experiment Video

Updated: May 22, 2026

Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

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[Comatose state--think different].

A Holbro¹, A Conen

¹Medizinische Poliklinik, Universitätsspital Basel, Switzerland. aholbro@uhbs.ch

|May 9, 2012

Summary

This summary is machine-generated.

A severe neurological condition, neuroborreliosis, can be reversed with prompt treatment. This case highlights the importance of accurate diagnosis for potentially reversible neurological impairments.

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Area of Science:

Neurology
Infectious Diseases
Medical Case Reports

Background:

Meningoencephalitis presents with inflammation of the brain and meninges.
Early diagnosis and treatment are crucial for managing neurological infections.

Observation:

A 76-year-old woman presented with meningoencephalitis and mononuclear pleocytosis.
Her condition worsened to a comatose state despite empirical antimicrobial treatment.

Findings:

Neuroborreliosis was confirmed serologically and via molecular biology.
Intravenous ceftriaxone therapy led to a slow but complete recovery.

Implications:

This case underscores the need for careful decision-making in treating potentially reversible neurological diseases.
Neuroborreliosis is identified as a treatable cause of severe neurological impairment.