Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Ocular toxoplasmosis in AIDS].

M Chakroun¹, M C Meyohas, B Pelosse

¹Groupe Hospitalier Bichat-Claude Bernard, Paris.

Annales De Medecine Interne

|January 1, 1990

Summary

Toxoplasmic retinochoroiditis is an increasing concern in AIDS patients, with diagnosis relying on eye exams and treatment response. Indefinite therapy is crucial to prevent relapses, and brain imaging is recommended for all affected individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

2010 French SPILF-AFSSAPS guiding criteria for Streptococcuspneumoniae acute community-acquired pneumonia: Evaluation in patients of the PACSCAN-ESCAPED cohort.

Infectious diseases now·2020

Same author

Multi-sectorial research is paramount for preventing and controlling emerging infectious diseases.

Revue d'epidemiologie et de sante publique·2019

Same author

Community-acquired pneumonia in the emergency department: an algorithm to facilitate diagnosis and guide chest CT scan indication.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019

Same author

Diabetes and dyslipidaemia are associated with oxidative stress independently of inflammation in long-term antiretroviral-treated HIV-infected patients.

Diabetes & metabolism·2019

Same author

Need for integrative thinking to fight against emerging infectious diseases. Proceedings of the 5th seminar on emerging infectious diseases, March 22, 2016 - current trends and proposals.

Revue d'epidemiologie et de sante publique·2017

Same author

The French Infectious Diseases Society's readiness and response to epidemic or biological risk-the current situation following the Middle East respiratory syndrome coronavirus and Ebola virus disease alerts.

Medecine et maladies infectieuses·2017

Area of Science:

Ophthalmology
Infectious Diseases
Neurology

Background:

Ocular toxoplasmosis, specifically toxoplasmic retinochoroiditis, is a growing opportunistic infection in patients with Acquired Immunodeficiency Syndrome (AIDS).
The incidence of ocular toxoplasmosis in AIDS patients showed an increasing trend from 1983 to 1988.
Diagnosis of toxoplasmic retinochoroiditis was challenging due to inconclusive antibody titers in aqueous humor.

Purpose of the Study:

To investigate the prevalence and diagnostic challenges of toxoplasmic retinochoroiditis in AIDS patients.
To emphasize the importance of long-term treatment to prevent relapse.
To highlight the association between ocular and cerebral toxoplasmosis in AIDS.

Main Methods:

Retrospective case series of 11 patients with toxoplasmic retinochoroiditis and AIDS from 1983 to 1989.

Related Experiment Videos

Diagnosis based on ophthalmoscopic criteria and response to anti-Toxoplasma gondii therapy.

Cerebral toxoplasmosis diagnosed using computerized tomography (CT) scans.

Main Results:

Eleven cases of toxoplasmic retinochoroiditis in AIDS patients were identified.
The prevalence of ocular toxoplasmosis in AIDS patients increased over the study period.
Seven out of 11 patients (63.6%) also had cerebral toxoplasmosis confirmed by CT scan.

Conclusions:

Toxoplasmic retinochoroiditis is a significant and potentially increasing manifestation of toxoplasmosis in AIDS patients.
Ophthalmoscopic examination and therapeutic response are key diagnostic tools when antibody titers are inconclusive.
Neurological evaluation and brain CT scans are recommended for all AIDS patients diagnosed with toxoplasmic retinochoroiditis due to the high co-occurrence of cerebral involvement.