Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neuroplasticity

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.

Cerebral Hemispheres

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

Lateralization

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.

Neurogenesis and Regeneration of Nervous Tissue

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A novel multifunctional NCQDs-based injectable self-crosslinking and in situ forming hydrogel as an innovative stimuli responsive smart drug delivery system for cancer therapy.

Materials science & engineering. C, Materials for biological applications·2021

Same author

To repeat or not to repeat: Radiologists demonstrated more decisiveness than their fellow radiographers in reducing the repeat rate during mobile chest radiography.

Radiography (London, England : 1995)·2020

Same author

Biomimetic synthesis of Ag, Zn or Co doped HA and coating of Ag, Zn or Co doped HA/fMWCNT composite on functionalized Ti.

Materials science & engineering. C, Materials for biological applications·2019

Same author

3D porous collagen/functionalized multiwalled carbon nanotube/chitosan/hydroxyapatite composite scaffolds for bone tissue engineering.

Materials science & engineering. C, Materials for biological applications·2018

Same author

Microwave-assisted biomimetic synthesis of hydroxyapatite using different sources of calcium.

Materials science & engineering. C, Materials for biological applications·2017

Same author

Association of SSR markers with contents of fatty acids in olive oil and genetic diversity analysis of an olive core collection.

Genetics and molecular research : GMR·2015

Search research articles

Related Experiment Video

Updated: May 22, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

Neuronal plasticity in a case with total hemispheric lesion.

M Ipek¹, H Hilal, T Nese

¹Marmara University Hospital, Department of Neurology, İstanbul, Turkey. ipekmidi@yahoo.com

Journal of Medicine and Life

|May 9, 2012

Summary

Early-life brain damage to the left hemisphere can be compensated by the right hemisphere, enabling functional recovery. This case demonstrates significant plasticity and adaptation despite extensive cerebral lesions.

Keywords:

Neuronal plasticity functional MRI hemispheric lesion reorganization

More Related Videos

Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies

Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies

Published on: December 15, 2014

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Published on: November 11, 2011

Related Experiment Videos

Last Updated: May 22, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies

Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies

Published on: December 15, 2014

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Published on: November 11, 2011

Area of Science:

Neuroscience
Neurology
Brain Plasticity

Background:

The adult brain exhibits lifelong plasticity, allowing for reorganization.
Non-invasive neuroimaging techniques like f-MRI and TMS can demonstrate functional recovery post-stroke.

Observation:

A 25-year-old female with extensive left hemisphere damage (encephalomalasia) presented with right-sided hemiparesis and homonymous hemianopia.
Despite severe motor and visual deficits, she maintained fluent speech and independence in daily living.
Functional MRI revealed right hemisphere activation during voluntary leg movements, indicating compensatory function.

Findings:

The case illustrates significant intra-hemispheric reorganization and neuronal plasticity following early-life cerebral lesions.
The unaffected right hemisphere compensated for the extensive damage to the left hemisphere, preserving speech and motor function.

Implications:

Early-life brain lesions can be compensated by the unaffected hemisphere through neuronal reorganization.
Patients with complete hemisphere lesions can achieve functional independence with potential for mild cognitive decline.