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Pediatric patients with intravascular devices: polymicrobial bloodstream infections and risk factors

Wes Onland1, Dasja Pajkrt, Cathy Shin

  • 1Department of Pediatrics, Emma Childrens Hospital, Academic Medical Center, P.O. Box 22700, 1100 DD Amsterdam, The Netherlands.

Journal of Pathogens
|May 9, 2012
PubMed

Insights

Younger patients with long-term intravascular devices (IVDs) face a higher risk of developing polymicrobial bloodstream infections (BSIs). This study highlights age as a key factor in BSI complexity in pediatric patients.

Area of Science:

  • Pediatric Infectious Diseases
  • Medical Device Infections
  • Clinical Microbiology

Background:

  • Catheter-related bloodstream infections (BSIs) are a significant concern in patients with long-term intravascular devices (IVDs).
  • Understanding the factors contributing to monomicrobial versus polymicrobial BSIs is crucial for effective treatment and prevention strategies.

Purpose of the Study:

  • To evaluate the incidence of monomicrobial and polymicrobial BSIs in pediatric patients with long-term IVDs.
  • To identify risk factors associated with polymicrobial BSIs in this patient population.

Main Methods:

  • A retrospective study of 61 pediatric patients with long-term IVDs and culture-proven BSIs.
  • Analysis of 125 catheter-related BSIs to determine the incidence of monomicrobial and polymicrobial infections.
  • Statistical evaluation to identify risk factors for polymicrobial BSIs.

Main Results:

  • Forty-two of 125 BSIs (33.6%) were polymicrobial.
  • Polymicrobial BSIs were more frequent in younger patients (under 4.1 years).
  • Use of venous implanted ports was associated with a lower incidence of polymicrobial BSIs.

Conclusions:

  • Younger age is a significant risk factor for developing polymicrobial BSIs in pediatric patients with long-term IVDs.
  • Further prospective research is needed to explore polymicrobial infections in IVDs more thoroughly.

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