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Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

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Related Experiment Video

Updated: May 22, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

[Old age workers].

N F Izmerov

    Meditsina Truda I Promyshlennaia Ekologiia
    |May 10, 2012
    PubMed
    Summary

    Leveraging the occupational potential of older workers through flexible schedules can boost workforce efficiency. Employment for seniors should align with their health and performance capabilities.

    Area of Science:

    • Gerontology
    • Labor Economics
    • Sociology of Aging

    Context:

    • Addressing demographic aging trends.
    • Meeting "Strategy 2020" goals for efficient resource utilization.
    • Recognizing the evolving nature of the workforce.

    Purpose:

    • To explore the occupational potential of older workers.
    • To propose strategies for engaging seniors in the workforce.
    • To inform policy on senior employment.

    Summary:

    • Flexible work arrangements like changeable schedules, outwork, and remote work can harness the skills of older employees.
    • Integrating seniors effectively requires considering individual performance, health status, and psycho-physiologic factors.
    • This approach contributes to efficient labor resource management amidst an aging population.

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    Evaluating the Function of the Foot Core System in the Elderly
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    Evaluating the Function of the Foot Core System in the Elderly

    Published on: March 11, 2022

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    Last Updated: May 22, 2026

    Oral Health Assessment by Lay Personnel for Older Adults
    08:47

    Oral Health Assessment by Lay Personnel for Older Adults

    Published on: February 2, 2020

    Evaluating the Function of the Foot Core System in the Elderly
    08:25

    Evaluating the Function of the Foot Core System in the Elderly

    Published on: March 11, 2022

    Impact:

    • Enhances workforce productivity and resource efficiency.
    • Promotes inclusive employment practices for older adults.
    • Supports national strategic objectives for labor market optimization.