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Updated: May 22, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Cytotoxic effect of some medicinal plants from Asteraceae family on J-45.01 leukemic cell line--pilot study
Magdalena Wegiera1, Helena D Smolarz, Marcin Jedruch
1Department of Pharmaceutical Botany, Medical University, 20-093 Lublin, Poland. m.wegiera@am.lublin.pl
Abstract:
In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell line was examined. All tested samples possess antileukemic properties and induce cells death via apoptosis. The correlation between antileukemic activity and total polyphenol content was determined.
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