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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
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[Estimation of pulse pressure in subjects with carbohydrate disorders]

Jan Kowalski1, Anna Brylik, Robert Irzmański

  • 1Uniwersytet Medyczny w Łodzi, III Katedra Rehabilitacji z Klinika Chorób Wewnetrznych i Rehabilitacji Kardiologicznej.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|May 10, 2012
PubMed

Insights

Pulse pressure is significantly higher in individuals with carbohydrate disorders. A pulse pressure of 52.5 mmHg or higher triples the risk of developing carbohydrate disorders.

Area of Science:

  • Cardiology
  • Endocrinology
  • Metabolic Disorders

Background:

  • Carbohydrate disorders are a significant risk factor for cardiovascular diseases.
  • Elevated pulse pressure is independently linked to cardiovascular complications and mortality.

Purpose of the Study:

  • To investigate the relationship between pulse pressure and carbohydrate disorders.
  • To determine if pulse pressure is a predictor of carbohydrate disorders.

Main Methods:

  • 112 subjects with carbohydrate disorders (impaired fasting glucose, impaired glucose tolerance, type 2 diabetes) and 30 controls were studied.
  • Fasting serum glucose and oral glucose tolerance tests were performed.
  • 24-hour ambulatory blood pressure monitoring was used to measure pulse pressure.

Main Results:

  • Mean pulse pressure was significantly higher in subjects with carbohydrate disorders (56.79 mmHg) compared to controls (49.0 mmHg).
  • Increased pulse pressure (> 63 mmHg) was observed more frequently in the carbohydrate disorder group (46% vs 10%).
  • Pulse pressure of 52.5 mmHg or higher was associated with a threefold increased risk of carbohydrate disorders.

Conclusions:

  • Elevated pulse pressure is significantly more prevalent in individuals with carbohydrate disorders.
  • Pulse pressure serves as a valuable indicator for the risk of developing carbohydrate disorders.
Abstract

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