Related Experiment Video
Updated: May 22, 2026
Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
[Analysis on changes of purgative biopotency in different processed products of rhubarb]
Huifang Li1, Jiabo Wang, Yi Qu
1Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China.
Objective:
To determine the difference on purgative biopotency of different processed products of rhubarb and compare rhubarb before and after preparation.
Method:
The prime biopotency of rhubarb reference substance was determined by comparing with the control substance of sennoside B using rat purgative model. Comparing with calibrated rhubarb reference substance, the bioactivity different processed products of rhubarb was determined by the 2,2',2" method.
Result:
The purgative biopotency of crude rhubarb was 825.22 U x g(-1). The purgative biopotency of alcohol-processed rhubarb was 699.05 U x g(-1), The purgative biopotency of steamed rhubarb were 459.76 U x g(-1). Carbonized rhubarb cannot be determinate.
Conclusion:
Crude rhubarb showed a significantly declineing purgative biopotency after being processed, alcohol-processed rhubarb showed less than crude rhubarb and followed by steamed rhubarb. Carbonized rhubarb lost almost all purgative bioactivity.
