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Updated: May 22, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

[Perinatal transmission of Chlamydia trachomatis and its complication in preterm infants]

Karolina Chojnacka1, Jerzy Szczapa, Witold Kedzia

  • 1Klinika Zakazeń Noworodków, Katedra Neonatologii UM im. K. Marcinkowskiego w Poznaniu, Polska. chojnaccy@gazeta.pl

Ginekologia Polska
|May 10, 2012
PubMed

Insights

Chlamydia trachomatis infection in pregnant women leads to a 75% perinatal transmission rate, causing severe respiratory issues in newborns. Early detection and intervention are crucial for preterm infants.

Area of Science:

  • Reproductive Health
  • Neonatal Medicine
  • Infectious Diseases

Context:

  • Chlamydia trachomatis is a common STI, posing risks during pregnancy.
  • Maternal infection can lead to premature delivery and neonatal complications like pneumonia and conjunctivitis.

Purpose:

  • To determine the rate of Chlamydia trachomatis perinatal transmission.
  • To assess the prevalence of neonatal complications associated with this infection.

Summary:

  • A study of 82 mothers and 100 newborns found Chlamydia trachomatis in 10% of mothers and 6 neonates.
  • Perinatal transmission occurred in 75% of cases, with all infected infants developing respiratory disorders, including apnea and requiring respiratory support.

Impact:

  • Highlights the significant risk of Chlamydia trachomatis transmission from mother to neonate.
  • Emphasizes the link between asymptomatic maternal infection and severe, potentially life-threatening respiratory complications in preterm infants.
Abstract

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