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Updated: May 22, 2026

Pyrosequencing for Microbial Identification and Characterization
Published on: August 22, 2013
Application of resequencing microarrays in microbial detection and characterization
Tomasz A Leski1, Baochuan Lin, Anthony P Malanoski
1Center for Bio/Molecular Science & Engineering, Naval Research Laboratory, SW, Washington, DC 20375, USA. tomasz.leski@nrl.navy.mil
Abstract:
Microarrays are powerful, highly parallel assays that are transforming microbiological diagnostics and research. The adaptation of microarray-based resequencing technology for microbial detection and characterization resulted in the development of a number assays that have unique advantages over other existing technologies. This technological platform seems to be especially useful for sensitive and high-resolution multiplexed diagnostics for clinical syndromes with similar symptoms, screening environmental samples for biothreat agents, as well as genotyping and whole-genome analysis of single pathogens.
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