Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Pharmacokinetics in Pediatric Patients: Drug Excretion

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children.

Diagnostic microbiology and infectious disease·2024

Same author

Racial/ethnic disparities in influenza risk perception and vaccination intention among Pima County residents in Arizona.

Human vaccines & immunotherapeutics·2022

Same author

Performance of Xpert MTB/RIF and Mycobacterial Culture on Multiple Specimen Types for Diagnosis of Tuberculosis Disease in Young Children and Clinical Characterization According to Standardized Research Case Definitions.

The Pediatric infectious disease journal·2022

Same author

The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis.

American journal of respiratory and critical care medicine·2022

Same author

Priority Activities in Child and Adolescent Tuberculosis to Close the Policy-Practice Gap in Low- and Middle-Income Countries.

Pathogens (Basel, Switzerland)·2022

Same author

Clinical outcomes of monoclonal antibody therapy during a COVID-19 outbreak in a skilled nursing facility-Arizona, 2021.

Journal of the American Geriatrics Society·2022

Search research articles

Related Experiment Video

Updated: May 22, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

Pediatric tuberculosis: new guidelines and recommendations.

Carlos M Perez-Velez¹

¹Grupo Tuberculosis Valle-Colorado, Division of Pediatric Infectious Diseases, Department of Pediatrics, Clínica León XIII IPS Universidad de Antioquia, Medellín, Antioquia, Colombia. CMPerezVelez@Gmail.com

Current Opinion in Pediatrics

|May 10, 2012

Summary

This summary is machine-generated.

Updated tuberculosis (TB) guidelines offer improved diagnostics and treatment for children, including novel tests for TB infection, drug resistance, and updated regimens for drug-resistant TB (DR-TB) and HIV-TB. Prevention strategies for HIV-infected children are also enhanced.

More Related Videos

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Related Experiment Videos

Last Updated: May 22, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Area of Science:

Pediatrics
Infectious Diseases
Public Health

Background:

Tuberculosis (TB) remains a significant global health challenge, particularly in pediatric populations.
Recent advancements in diagnostics and treatment necessitate updated guidelines for effective TB management in children and adolescents.
Supranational organizations play a crucial role in disseminating evidence-based recommendations for TB control.

Purpose of the Study:

To review and synthesize new and updated tuberculosis (TB) guidelines published since 2010.
To focus on recommendations relevant to infants, children, and adolescents.
To emphasize guidelines from supranational health organizations.

Main Methods:

Systematic review of recent tuberculosis (TB) guidelines.
Analysis of recommendations concerning pediatric TB diagnosis, treatment, and prevention.
Synthesis of findings related to novel diagnostics and updated therapeutic regimens.

Main Results:

Novel diagnostics for TB infection, disease, and drug resistance have been developed.
Updated treatment regimens for childhood and drug-resistant TB (DR-TB) are now available.
Primary and secondary prevention strategies for TB in HIV-infected children and adolescents have been refined.

Conclusions:

New guidelines significantly improve pediatric TB care, offering complementary diagnostic roles for interferon-gamma release assays alongside tuberculin skin testing.
Validated polymerase chain reaction and line probe assays enhance the detection of Mycobacterium tuberculosis and drug resistance, especially in high-risk groups.
Updated World Health Organization treatment recommendations address various clinical syndromes, multidrug-resistant TB, and HIV/TB co-infection, alongside new prevention algorithms and secondary prophylaxis for HIV-infected children.