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Related Concept Videos

Strain-Energy Density01:20

Strain-Energy Density

Understanding the strain energy density in materials under axial load is crucial for evaluating their mechanical behavior and durability. When a rod is subjected to such a load, it elongates and stores energy, known as strain energy, as potential energy within the material. This energy is measured in terms of energy per unit volume.
In the elastic region of a material, the relationship between the stress and the strain is linear and follows Hooke's Law. The strain energy density in this region...

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Related Experiment Video

Updated: May 22, 2026

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model
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Is packing density important in stent-assisted coiling?

Nohra Chalouhi1, Aaron S Dumont, David Hasan

  • 1Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania 19107, USA.

Neurosurgery
|May 10, 2012
PubMed
Summary
This summary is machine-generated.

Stent-assisted coiling (SAC) achieves high obliteration rates for brain aneurysms. Moderate and high packing densities (PD) yield similar outcomes, suggesting high PD is not always necessary in SAC.

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Last Updated: May 22, 2026

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model
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08:28

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Published on: May 8, 2012

Area of Science:

  • Neurosurgery
  • Interventional Neuroradiology
  • Cerebrovascular Disease

Background:

  • Stent-assisted coiling (SAC) shows lower recanalization rates than conventional coiling.
  • This raises questions about the necessity of high packing density (PD) in stented aneurysms.

Purpose of the Study:

  • To evaluate the impact of PD on follow-up obliteration rates in stented aneurysms.
  • To determine the optimal PD range for SAC procedures.

Main Methods:

  • Retrospective analysis of 292 SAC procedures over 5 years.
  • Comparison of complete obliteration rates across high (>22%), moderate (12-22%), and low (<12%) PD groups.
  • Use of Neuroform and Enterprise stents in a single cerebrovascular referral center.

Main Results:

  • Complete obliteration rate was 79.5% at latest follow-up.
  • Moderate and high PD groups showed significantly higher obliteration rates than the low PD group (86.4% and 85.3% vs. 71.1%).
  • No significant difference in obliteration rates was found between moderate and high PD groups. PD, smaller aneurysm volume, and non-ruptured status predicted obliteration.

Conclusions:

  • High obliteration rates are achievable with moderate PD in stented aneurysms.
  • Both moderate and high PD provide equivalent angiographic obliteration rates in SAC.
  • PD is a significant factor, but excessive packing may not be required.