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Updated: May 22, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Novel sensory signaling systems in the kidney
Jennifer L Pluznick1, Michael J Caplan
1Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Purpose Of Review:
This review summarizes recent literature highlighting the roles of chemical and mechanical sensory receptors in renal function.
Recent Findings:
Both chemoreceptors and mechanoreceptors play important roles in renal physiology; here, we discuss specific examples of both chemoreceptors and mechanoreceptors in the kidney.
Summary:
In order to maintain homeostasis, the kidney uses sensory receptors to assess the composition and rate of flow of the forming urine. Understanding the roles of these receptors will help us to better understand how the kidney functions both in health and in disease.
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