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Fox-Fordyce disease: response to adapalene 0.1%
Luiza Erthal de Britto Pereira Kassuga1, Mariana Malta Medrado, Natalia Stroligo Chevrand
1Dermatology Service of the Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, RJ, Brazil. luizakassuga@yahoo.com.br
Anais Brasileiros De Dermatologia
|May 10, 2012
Summary
Fox-Fordyce disease, a rare itchy skin condition, significantly improved with topical adapalene 0.1%. This treatment offers a promising option for managing this inflammatory dermatosis affecting apocrine gland areas.
Area of Science:
- Dermatology
- Histopathology
Background:
- Fox-Fordyce disease is a rare inflammatory dermatosis.
- It primarily affects young women, presenting as itchy, follicular papules in apocrine gland-rich areas.
- Histopathology reveals spongiosis, fibrosis, and lymphohistiocytic infiltrate.
Purpose of the Study:
- To evaluate the efficacy of adapalene 0.1% in treating Fox-Fordyce disease.
- To assess the improvement in clinical signs and symptoms.
Main Methods:
- Clinical and histopathological diagnosis of Fox-Fordyce disease.
- Topical application of adapalene 0.1% was administered.
- Observed and recorded signs and symptoms improvement.
Main Results:
- Satisfactory improvement in the signs and symptoms of Fox-Fordyce disease was observed.
- Adapalene 0.1% demonstrated positive therapeutic effects.
Conclusions:
- Topical adapalene 0.1% is an effective treatment option for Fox-Fordyce disease.
- Further research may explore its role in managing this condition.
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