Related Experiment Video

Updated: May 22, 2026

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

Febrile seizures: an epidemiological and outcome study of 482 cases

Lamia Sfaihi1, Ines Maaloul, Sana Kmiha

  • 1Department of Pediatrics, Hedi Chaker Hospital, Sfax, Tunisia. sfaihilamia@yahoo.fr

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|May 10, 2012
PubMed

Insights

Febrile seizures (FSs) in children rarely lead to epilepsy, though recurrence is possible. Family history, young age, and low fever predict recurrent FSs, but long-term risks are minor.

Area of Science:

  • Pediatrics
  • Neurology

Background:

  • Febrile seizures (FSs) are common in children.
  • 1-12% of children with FS develop epilepsy; 30% have recurrent FSs.

Purpose of the Study:

  • Describe epidemiological aspects of FS.
  • Define long-term outcomes for children with first FS.
  • Identify risk factors for FS recurrence and epilepsy development.

Main Methods:

  • Retrospective study of 482 children with FS.
  • Data collected from January 2004 to December 2009.
  • Medical records analyzed for outcomes and risk factors.

Main Results:

  • 55.2% had simple FSs, 44.8% complex FSs.
  • Mean follow-up: 2 years 4 months (range 1-5 years).
  • 1% developed epilepsy; 11.7% experienced recurrent seizures.
  • Predictors for recurrence: family history, young age, low fever.

Conclusions:

  • Children with FSs have low risk of mortality and morbidity.
  • Recurrent seizures occur in a minority of cases.
  • Epilepsy development is infrequent following FS.
Abstract

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