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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Related Experiment Video

Updated: May 22, 2026

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Skin graft.

Ruka Shimizu1, Kazuo Kishi

  • 1Department of Plastic and Reconstructive Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan.

Plastic Surgery International
|May 10, 2012
PubMed
Summary

Skin grafting is a vital surgical technique for plastic surgery and dermatology, addressing various conditions from wounds to reconstructions. This review details successful skin grafting methods and variations.

Area of Science:

  • Plastic Surgery
  • Dermatology
  • Wound Healing

Background:

  • Skin grafting is a fundamental procedure in plastic surgery and dermatology.
  • It is utilized for diverse clinical applications including traumatic wounds, post-oncologic defects, burn reconstruction, scar release, congenital deficiencies, hair restoration, vitiligo, and nipple-areola reconstruction.

Purpose of the Study:

  • To provide a comprehensive overview of successful skin grafting techniques.
  • To discuss variations in skin grafting procedures.

Main Methods:

  • Review of existing literature and established surgical practices for skin grafting.
  • Description of procedural steps and considerations for successful outcomes.

Main Results:

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Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
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Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

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A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
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A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Published on: August 8, 2020

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Last Updated: May 22, 2026

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
08:23

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Published on: June 29, 2022

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
12:18

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Published on: August 8, 2020

  • Skin grafting is a versatile technique applicable to a wide range of dermatological and surgical defects.
  • Complex wounds with exposed bone or deep spaces typically necessitate flap procedures over grafts.

Conclusions:

  • Successful skin grafting requires understanding its indications and proper technique.
  • This review serves as a guide to performing skin grafting effectively and exploring its variations.