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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

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Related Experiment Video

Updated: May 22, 2026

Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
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Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia

Published on: June 26, 2020

Tracking stem cells for cellular therapy in stroke.

Nathan C Manley1, Gary K Steinberg

  • 1Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro-Innovation and Translational Neurosciences, Stanford University School of Medicine, 300 Pasteur Drive Stanford, California, CA 94305-5327, USA.

Current Pharmaceutical Design
|May 11, 2012
PubMed
Summary

Monitoring transplanted stem cells is crucial for stroke recovery. This review covers optical imaging, MRI, and PET for tracking stem cells, aiding clinical advancement.

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Last Updated: May 22, 2026

Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
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Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain
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Published on: January 27, 2022

Area of Science:

  • Neuroscience
  • Regenerative Medicine
  • Medical Imaging

Background:

  • Stem cell transplantation shows promise for stroke treatment.
  • Effective monitoring of transplanted stem cells is vital for understanding stroke recovery mechanisms.
  • Advancing stem cell therapy to clinical practice requires reliable tracking methods.

Purpose of the Study:

  • To review current in vivo methods for tracking transplanted stem cells after stroke.
  • To discuss the advantages and disadvantages of various imaging techniques.
  • To evaluate the impact of tracking systems on stem cell function and human applicability.

Main Methods:

  • Review of existing literature on stem cell tracking methods.
  • Analysis of optical imaging, magnetic resonance imaging (MRI), and positron emission tomography (PET).
  • Discussion of multi-modal imaging strategies.

Main Results:

  • Optical imaging, MRI, and PET offer different benefits and drawbacks for stem cell tracking.
  • Considerations include effects on stem cell function and human applicability.
  • Multi-modal imaging presents a comprehensive approach.

Conclusions:

  • Accurate tracking of transplanted stem cells is essential for stroke therapy development.
  • Choosing the right imaging modality depends on specific research and clinical needs.
  • Integrated imaging strategies can provide a more complete picture of stem cell behavior in the stroke-injured brain.