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Updated: May 22, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Isoniazid-induced recurrent pancreatitis
Sarah Mattioni1, Michele Zamy, Frederic Mechai
1Department of Infectious Diseases, University of Paris 13. Bobigny, France. mattionis@yahoo.fr
Context:
Drug induced pancreatitis are rare but potentially serious. Thus, drug withdrawal is warranted.
Case Report:
A 79-year-old woman who was treated with antituberculosis therapy for 5 weeks was admitted to our unit for pancreatitis. Usual etiologies of pancreatitis were eliminated. Because of vomiting, antituberculosis therapy was withdrawn and symptoms disappeared. Eight days later, the same treatment was reintroduced and the patient presented recurrent pancreatitis; thus, treatment was withheld again followed by disappearance of clinical and biological abnormalities. Two days later, a treatment without isoniazid was reintroduced and no recurrence of symptoms was observed.
Conclusions:
We have experienced a case of isoniazid induced pancreatitis. This is a rare cause of pancreatitis but potentially fatal thus recognition of drug induced pancreatitis and definitive withdrawal of the drug is required.
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