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Inferior vena cava obstruction: long-term results of endovascular management
B C Srinivas1, P V Dattatreya, K H Srinivasa
1Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, India. lotusheart7@gmail.com
Insights
Endovascular management of chronic inferior vena cava (IVC) obstruction is a safe and effective treatment. This minimally invasive approach offers good long-term patency rates for hepatic venous outflow obstruction (HVOO).
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Hepatology
Background:
- Hepatic venous outflow obstruction (HVOO) presents acutely or chronically.
- Chronic inferior vena cava (IVC) obstruction can be managed with endovascular techniques, offering a safer alternative to surgery.
- Surgical intervention for IVC obstruction carries high risks of mortality and morbidity.
Purpose of the Study:
- To evaluate the feasibility of endovascular management for chronic IVC obstruction.
- To assess the long-term follow-up outcomes of endovascular treatment for HVOO.
Main Methods:
- Twelve patients with HVOO underwent endovascular procedures, including balloon angioplasty and stenting.
- Diagnosis involved clinical examination, venous Doppler, venography, and CT angiography.
- Causes of obstruction included membranous obstruction, segmental stenosis, and tumor compression.
Main Results:
- All 12 cases achieved procedural success.
- Endovascular treatment resulted in an 84% gradient reduction and collateral disappearance.
- Follow-up over 13 years showed good long-term patency, with one case of restenosis successfully managed by stenting.
Conclusions:
- Endovascular management is a safe and effective treatment for chronic IVC obstruction.
- The procedure demonstrates favorable long-term patency rates.
- This approach provides a viable alternative to surgery for HVOO.
Background:
Hepatic venous outflow obstruction (HVOO) can have acute or chronic presentation. In the chronic variety of inferior vena cava (IVC) obstruction, endovascular management with balloon angioplasty and stent implantation has emerged as a feasible, safe alternative to surgery which has high incidence of mortality and morbidity.
Aims And Objectives:
To study the feasibility and long-term follow-up of endovascular management of chronic IVC obstruction.
Methods:
We studied 12 cases of HVOO who underwent endovascular management (balloon dilatation ± stenting). In most of the cases, the cause of obstruction was not obvious, but one case had metastatic hepatic nodules compressing on IVC. Diagnosis was established by clinical examination, venous Doppler and was confirmed by venography and/or computed tomography (CT) angiography. Cases underwent balloon dilatation and/or stenting.
Results:
Out of 12 cases, six had membranous obstruction (four complete and two incomplete), five cases had segmental stenosis and one case had tumour compression. The lesion was crossed with either guide wire or Brockenbrough needle with Mullins sheath assembly and balloon dilatation was done with Inoue or Mansfield balloon. Seven cases underwent balloon dilatation alone while five cases underwent stenting. There was procedural success in all cases with reduction of gradient by 84%, disappearance of collaterals and clinical improvement. During the follow-up of 13 years, one case had restenosis, which was managed by stenting.
Conclusion:
Endovascular management of IVC obstruction is safe with good long-term patency rates.
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