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Related Concept Videos

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Drug Toxicity: Risk factors

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Chronic Kidney Disease II: Clinical Manifestations

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Updated: May 22, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Clinical presentation and risks.

Gian Andrea Binda1, Antonio Amato, Alberto Serventi

  • 1Department of General Surgery, Galliera Hospital, Genova, Italy. gian.andrea.binda@galliera.it

Digestive Diseases (Basel, Switzerland)
|May 11, 2012
PubMed
Summary
This summary is machine-generated.

Recurrent diverticulitis has a lower recurrence rate and less severe outcomes than previously thought. Conservative treatment is effective, with low risks of complications and death, not supporting aggressive surgery.

Related Experiment Videos

Last Updated: May 22, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

  • Gastroenterology
  • Surgical Gastroenterology
  • Clinical Epidemiology

Background:

  • Recurrent diverticulitis, defined as new acute inflammation after remission, was historically associated with high recurrence rates (>40%) and severe presentations.
  • Outdated literature suggested a need for aggressive treatment, but recent studies indicate a more benign clinical course.

Purpose of the Study:

  • To evaluate the recurrence rate and long-term outcomes of acute diverticulitis (AD) treated conservatively.
  • To determine if an aggressive surgical policy is necessary for preventing complications of recurrent AD.

Main Methods:

  • A 4-year multicenter analysis of 743 patients hospitalized for AD, with revised literature review and a prospective/retrospective database.
  • Follow-up of 320 medically treated patients for a minimum of 9 years, analyzing recurrence, emergency surgery, stoma, and death rates.

Main Results:

  • Literature review indicated a 25-35% recurrence rate at 5 years with low risks of severe complications (2-14% emergency surgery, 0-2.7% stoma/death).
  • In the study cohort, the 12-year actuarial risk of recurrence, emergency surgery, stoma, and death was 21.2%, 8.3%, 1%, and 0%, respectively.
  • Recurrence was linked to very young age (<40 years) and >3 previous AD episodes; 61% remained asymptomatic, 22% had chronic symptoms.

Conclusions:

  • Conservative management of acute diverticulitis leads to a benign long-term course with low risks of serious complications and death.
  • Findings do not support an aggressive surgical approach for preventing complications in patients with recurrent diverticulitis.