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Ventricular width and complicated recovery following deep brain stimulation surgery
Sarah K Bourne1, Andrew Conrad, Peter E Konrad
1Department of Neurology Vanderbilt University Medical Center, Nashville, TN, USA. sarah.k.bourne@vanderbilt.edu
Stereotactic and Functional Neurosurgery
|May 11, 2012
Summary
Preoperative lateral ventricle width measurements can help predict complications after deep brain stimulation (DBS). Larger ventricle widths indicate a higher risk of confusion, complex discharge, and other adverse events following DBS surgery.
Area of Science:
- Neurosurgery
- Radiology
- Medical Imaging
Background:
- Deep brain stimulation (DBS) requires careful patient selection to mitigate risks.
- Existing methods for predicting DBS complications are imperfect.
Purpose of the Study:
- To investigate if linear measurements of lateral ventricles predict complications after DBS.
- To identify novel imaging biomarkers for DBS outcomes.
Main Methods:
- Retrospective analysis of DBS patients and matched controls.
- Measurement of lateral ventricle width from preoperative MRI scans.
- Primary outcome: postoperative confusion; secondary outcomes: discharge disposition, in-hospital complications.
Main Results:
- Patients with postoperative confusion had significantly wider lateral ventricles.
- Wider ventricles correlated with higher-level discharge and increased overall complications.
- Ventricular width measurements showed a significant difference between cases and controls.
Conclusions:
- Preoperative lateral ventricle width is a potential predictor of complicated recovery after DBS.
- Measurement of ventricular dimensions may aid in patient risk stratification for DBS.
- This finding could improve preoperative assessment and patient counseling for DBS procedures.

