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Activity of telavancin compared to other agents against coagulase-negative staphylococci with different resistotypes
Gengrong Lin1, Glenn A Pankuch, Peter C Appelbaum
1Hershey Medical Center, Hershey, PA 17033, USA
Abstract:
Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4× MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By contrast, linezolid was mainly bacteriostatic and teicoplanin was bactericidal to 7 strains tested at 4× MIC after 24 h.
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