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Updated: May 22, 2026

Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate
Published on: December 12, 2015
Metabolic acidosis during treatment of mushroom poisoning: a diagnostic pitfall
Nikolaos K Gatselis1, George Liamis, Konstantinos P Makaritsis
1Department of Medicine and Research Lab of Internal Medicine, Thessaly University Medical School, Greece. ngatsel@med.uth.gr
Abstract:
Metabolic acidosis is a frequently encountered acid-base disturbance in hospitalized patients that occasionally develops in the course of treatment with medications used in everyday clinical practice, including propylene glycol-containing drugs (lorazepam, diazepam, etomidate, pentobarbital). Disruption of enterohepatic circulation with activated charcoal is a common practice for several intoxications, including mushroom poisoning. Herein, we present a patient who was hospitalized due to mushroom intoxication and developed severe metabolic acidosis as a treatment side effect rather than from the mushroom poisoning. To the best of our knowledge, this is the first report on propylene glycol-containing activated charcoal-induced metabolic acidosis.
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