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Periodontitis as a risk factor in non-diabetic patients with coronary artery disease

Vida Nesarhoseini1, Mahmoud Khosravi

  • 1MD, Department of Cardiology, Mazandaran University of Medical Science, Sari, Iran.

ARYA Atherosclerosis
|May 12, 2012
PubMed

Insights

Gingival inflammation, known as periodontitis, is a significant risk factor for coronary artery disease (CAD) in individuals over 40. This study found a strong association between periodontitis and CAD in patients with confirmed coronary artery disease.

Area of Science:

  • Cardiology
  • Periodontology
  • Public Health

Background:

  • Coronary artery disease (CAD) is a leading cause of mortality worldwide.
  • Conventional risk factors explain only 50-70% of atherosclerotic events.
  • An unexplored link may exist between periodontal disease and CAD.

Purpose of the Study:

  • To investigate the relationship between prevalent coronary artery disease (CAD) and clinical periodontal disease.
  • To assess periodontal health in patients with angiographically proven CAD.

Main Methods:

  • 152 consecutive patients with angiographically proven CAD were included.
  • Each patient underwent a comprehensive periodontal examination during their visit.

Main Results:

  • Patients with CAD exhibited significantly higher plaque index (2.46±0.62) and bleeding index (1.86±0.92) compared to those with normal coronaries.
  • Mean adhesion levels were also significantly higher in patients with CAD (4.13±1.45).
  • Probe depth showed a borderline relation to cardiovascular disease (p=0.051).

Conclusions:

  • Gingival inflammation (periodontitis) is a significant risk factor for coronary artery disease in individuals over 40.
  • Periodontal disease is strongly associated with angiographically proven coronary artery disease.
Abstract

Keywords:
Coronary angiographyCoronary artery disease (CAD)Gingival. inflammation (periodontitis)

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