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Systemic thrombolysis in the upper extremity deep vein thrombosis
1Assistant Professor of Cardiology, Cardiovascular Research Center, Department of Internal Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences (SUMS), Tehran, Iran.
ARYA Atherosclerosis
|May 12, 2012
Summary
Upper extremity deep vein thrombosis (UEDVT) affects nearly 4% of patients with venous thrombosis and can lead to significant post-thrombotic syndrome (PTS). This review briefly discusses thrombolytic therapy options for UEDVT.
Area of Science:
- Vascular Medicine
- Thrombosis Research
Background:
- Upper extremity deep vein thrombosis (UEDVT) represents a growing clinical concern, affecting approximately 4% of all venous thrombosis cases.
- The incidence of UEDVT is increasing, highlighting its rising prevalence.
- Post-thrombotic syndrome (PTS) following UEDVT is a significant complication, potentially causing major morbidity and reduced quality of life, especially when the dominant arm is affected.
Purpose of the Study:
- To review the current understanding of upper extremity deep vein thrombosis (UEDVT).
- To briefly discuss the therapeutic role of thrombolytic therapy in managing UEDVT.
- To explore the application of systemic thrombolysis in selected UEDVT patients.
Main Methods:
- Literature review focusing on upper extremity deep vein thrombosis.
- Discussion of existing treatment modalities for UEDVT.
- Analysis of the role of thrombolytic agents in UEDVT management.
Main Results:
- UEDVT is an increasingly recognized condition with a notable frequency.
- Post-thrombotic syndrome (PTS) is a common and serious sequela of UEDVT.
- Thrombolytic therapy, including systemic thrombolysis, is considered for specific patient groups with UEDVT.
Conclusions:
- Upper extremity deep vein thrombosis (UEDVT) is a significant vascular condition associated with considerable risk of post-thrombotic syndrome (PTS).
- The management of UEDVT may involve thrombolytic strategies in carefully selected individuals.
- Further research into optimal UEDVT treatment is warranted to mitigate long-term morbidity.
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