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Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Percutaneous transluminal angioplasty in a patient with vasospasm due to staphylococcal meningitis
David Buechner1, Michael S Gelfand, Kerry O Cleveland
1Department of Radiology, Methodist Healthcare of Memphis, University of Tennessee Health Science Center, Memphis, TN 38104, USA.
Abstract:
Arterial large vessel vasculopathy is an unusual complication of bacterial meningitis in adults that may result in cerebral ischemia and severe neurological sequelae. Previous therapy has included antimicrobials with no specific vascular interventions. The authors report their experience with a patient with bacterial meningitis who developed a vasculopathy with neurological deficits. Percutaneous intracranial intervention was used successfully with anatomical and functional improvement.
Insights
Bacterial meningitis can cause unusual arterial large vessel vasculopathy, leading to stroke. This case study shows successful treatment using percutaneous intracranial intervention, improving neurological deficits.
Area of Science:
- Neurology
- Vascular Medicine
- Infectious Diseases
Background:
- Bacterial meningitis can lead to arterial large vessel vasculopathy.
- This complication may cause cerebral ischemia and severe neurological deficits.
- Current treatments focus on antimicrobials, lacking specific vascular interventions.
Observation:
- A case of bacterial meningitis with associated vasculopathy and neurological deficits is presented.
Findings:
- Percutaneous intracranial intervention was successfully employed.
- The intervention led to both anatomical and functional improvement in the patient.
Implications:
- Percutaneous intracranial intervention offers a potential therapeutic strategy for bacterial meningitis-induced vasculopathy.
- This approach may improve outcomes for patients experiencing severe neurological sequelae.
- Further research into endovascular techniques for managing infectious vasculitis is warranted.
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