One new antitumour cassane-type diterpene from Caesalpinia crista
Qi-Jian Tian1, Yang-Hui Ou, Xing-Bing He
1Key Laboratory of Plant Resources Conservation and Utilization of Hunan Province, Jishou University, Jishou 416000, China. tianqijian68@163.com
Natural Product Research
|May 15, 2012
Abstract:
1α-acetoxy-5α, 7β-dihydroxycassa-11,13(15)-diene-16,12-lactone, a new cassane-type diterpene was isolated from Caesalpinia crista. The structure of this compound was elucidated by analysis of NMR spectra, and the relative configuration was established by NOE experiment. The new compound was evaluated for antitumour activity against T47D, DU145 and showed significant inhibitory activities.
