Related Experiment Video
Updated: May 22, 2026
07:18
Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
Published on: January 9, 2026
Perosomus elumbis in a puppy
C B Amaral1, M A P Romão, A M R Ferreira
1Departamento de Medicina Veterinária, Faculdade de Medicina Veterinária, Universidade Federal do Espírito Santo, 29500-000 Alegre, ES, Brazil. camilaosso@gmail.com
Journal of Comparative Pathology
|May 15, 2012
Summary
This study details a rare congenital anomaly in a poodle puppy, perosomus elumbis, characterized by severe hindlimb malformations and vertebral defects. The condition resulted in significant developmental abnormalities across multiple organ systems.
Area of Science:
- Veterinary Pathology
- Developmental Biology
- Canine Genetics
Background:
- Congenital anomalies in domestic animals present diagnostic and ethical challenges.
- Perosomus elumbis is a rare, severe congenital defect affecting spinal development.
- Understanding the etiology and manifestations of such conditions is crucial for veterinary medicine.
Observation:
- A 2-day-old poodle puppy presented with hypoplastic, arthrogrypotic hindlimbs and an absent tail.
- Physical examination revealed a lack of lumbar and sacral vertebrae.
- Necropsy confirmed severe developmental defects, including absent urinary and genital systems, a truncated spinal cord, and abnormal pelvic structure.
Findings:
- The puppy exhibited perosomus elumbis, a severe congenital anomaly characterized by the absence of the caudal vertebral column and associated structures.
- Associated malformations included a malformed gastrointestinal tract (blind-ending colon), absent urinary and reproductive systems, and a truncated spinal cord.
- Skeletal abnormalities were profound, with pelvic malformation and lack of spinal articulation.
Implications:
- This case highlights the extreme end of congenital vertebral and limb malformations in canines.
- Further research into the genetic and environmental factors contributing to perosomus elumbis is warranted.
- Accurate diagnosis and understanding of such rare conditions are vital for prognosis and genetic counseling in affected breeds.
