Related Experiment Video
Updated: May 22, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Meningitis can resemble subarachnoid haemorrhage]
1Neurologisk Afdeling, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark. nour059@hotmail.com
Abstract:
A 70 year-old man was admitted under the diagnosis of subarachnoid haemorrhage and presented with a history of ear pain, followed by acute onset of severe headache, nausea, vomiting, impaired consciousness, and fever. However, a computed tomography (CT) showed an acute mastoiditis and pneumocephalus, and a lumbar puncture confirmed the diagnosis meningitis. The increased middle ear pressure relative to the intracranial pressure had caused air and bacteria to penetrate intracerebrally. This case illustrates the importance of a rapid diagnostic workup in acute onset headache including a careful anamnesis, CT and lumbar puncture.
Insights
A 70-year-old man with ear pain developed meningitis due to bacteria entering the brain from acute mastoiditis. Rapid diagnosis involving CT scans and lumbar puncture is crucial for severe headaches.
Area of Science:
- Neurology
- Infectious Diseases
- Otolaryngology
Background:
- Subarachnoid hemorrhage is a critical condition often presenting with severe headache.
- Acute mastoiditis, an infection of the mastoid bone, can lead to serious intracranial complications.
Observation:
- A 70-year-old male presented with symptoms mimicking subarachnoid hemorrhage, including headache, nausea, vomiting, altered consciousness, and fever.
- Initial computed tomography (CT) revealed acute mastoiditis and pneumocephalus (air in the skull).
Findings:
- Lumbar puncture confirmed meningitis, indicating infection of the brain's protective membranes.
- The case suggests that increased middle ear pressure in mastoiditis allowed intracranial penetration of air and bacteria.
Implications:
- This case highlights the necessity of a comprehensive diagnostic approach for acute onset headaches.
- Early integration of neuroimaging (CT) and cerebrospinal fluid analysis (lumbar puncture) is vital for accurate diagnosis and timely treatment.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology
Viral Meningitis
Hemorrhagic Stroke l: Introduction
Brain Abscess l: Introduction

