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[Stability of metronidazole, prednisolone and dexamethasone in urea-containing Elacutan W dermatologic agent]
R Heyde1, S Dorsch, S Heidenreich
1Zentralapotheke, Bereichs Medizin, Martin-Luther-Universität Halle-Wittenberg.
Dermatologische Monatschrift
|January 1, 1990
Abstract:
Metronidazole was investigated in the basic dermatologic agent Elacutan W to improve the topical therapy of rosacea. The suitability of that basic dermatologic agent was verified for metronidazole, prednisolone and dexamethasone by stability tests (UV-spectroscopy, pH) and by in-vitro-liberation-measurements (membrane method). The drugs are stable for a period of 100 days.