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[Histopathological findings in Hodgkin's disease (author's transl)]
Abstract:
The histological classification of Hodgkin's disease, as proposed by Lunkes and Butler, is incomplete and does not include all the morphological findings. The distinction between sub-varieties of the nodular sclerosing type and particular forms of the disease (interfollicular with necrosis, with xanthelasma, or epithelioid pseudo-metastatic cells) clearly demonstrates the large polymorphism of the ganglionic lesions. A study of the different types encountered in the same patient shows that there is probably a form which evolves from type 1 towards type 3 and then type 4, an another form characterized by nodular sclerosis. The distribution of the various varieties and sub-varieties were studied by the author in 442 ganglia and results were similar to those reported in other series: nodular sclerosing form: 38.2%; form without nodular sclerosis: 61.8% made up of H1: 10.6%, H3: 45.5%, H4: 5.6%.