Related Experiment Video
Updated: May 22, 2026
04:25
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Late-onset fracture-associated osteosarcoma in a cat
B Sonnenschein1, M J Dickomeit, M S Bali
1Small Animal Hospital, Stommeln, Germany.
Summary
A rare feline osteosarcoma developed 17 years after a femoral fracture repair in an 18-year-old cat. This fracture-associated bone cancer highlights unusual late-onset presentations.
Area of Science:
- Veterinary Medicine
- Oncology
- Orthopedics
Background:
- Osteosarcoma is a common primary bone tumor in dogs, but less frequent in cats.
- Fracture-associated tumors are rare, particularly in older animals with a history of orthopedic repair.
Observation:
- An 18-year-old castrated Domestic Shorthaired cat presented with severe left pelvic limb lameness.
- Radiographs revealed a displaced distal femoral fracture with bone lysis and periosteal proliferation, suggesting a pathological process.
- A previous repair of a distal physeal femoral fracture from 17 years prior was noted.
Findings:
- Histopathology confirmed appendicular osteosarcoma.
- The tumor was associated with the site of the old fracture, indicating a fracture-associated osteosarcoma.
- The cat underwent successful amputation and recovered fully without complications.
Implications:
- This case demonstrates an unusual late-onset presentation of fracture-associated feline osteosarcoma.
- It underscores the importance of considering neoplasia in older animals with non-traumatic fractures or signs of bone lysis near old fracture sites.
- Further research into the pathogenesis of fracture-associated osteosarcoma in felines may be warranted.
