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Resveratrol and health: the starting point
Lucia Biasutto1, Andrea Mattarei, Mario Zoratti
1CNR Institute of Neuroscience and Department of Biomedical Sciences, University of Padova, Viale Giuseppe Colombo 3, 35131 Padova, Italy.
Chembiochem : a European Journal of Chemical Biology
|May 15, 2012
Abstract:
Cascade of youth? Resveratrol, the celebrated phytoalexin of red wine, was known to activate AMPK indirectly, but how this happened was unclear. In a paper recently published in Cell, S.-J. Park, J. H. Chung and co-workers identify the signalling cascade, which begins with the inhibition of phosphodiesterases, in particular PDE4. But questions remain, even while new perspectives open up.
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